Keywords:
breast conserving surgery, excision, 3D imaging, image reconstruction, tomosynthesis, digital breast tomosynthesis, specimen
Breast conserving surgery involves an excision procedure to achieve clear margins. This goal is usually achieved by performing intraoperative margin assessment with specimen imaging and immediate excision of any margins thought to be close or positive. However, routine two-dimensional specimen radiography cannot clearly discern residual disease at the margins. Quasi-three-dimensional digital breast tomosynthesis potentially increases sensitivity but still cannot sufficiently meet the need, due to the limitation of its cross-sectional in-plane images. We propose a novel tomographic technique that uses limited-angle tomosynthesis projections to reconstruct 3D transverse images. A simulation study was performed based on the geometry of a commercial DBT system to demonstrate the feasibility. The proposed tomographic technique will have the potential to more effectively guide surgeons to precisely remove the tumor with a clear margin and better cosmetic result, significantly reducing the need for a return to the operating room
- Qingsong Yang
- Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
- Ge Wang
- Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
- Gary Ge
- Department of Radiology, College of Medicine University of Kentucky
- Xiaoqin Wang
- Department of Radiology, College of Medicine University of Kentucky
- Jie Zhang
- Department of Radiology, College of Medicine University of Kentucky
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