Keywords:
L-shell XFCT, Monte Carlo simulation, pinhole collimator
As a novel imaging method, X-ray fluorescence computed tomography (XFCT) has attracted wide concern in recent years. In this paper, a polychromatic L-shell XFCT with pinhole collimator was proposed to save scanning time and improve detection limit of imaging system. First, imaging theoretical formulas were derived. Then, two phantoms (A and B) filled with polymethyl methacrylate (PMMA) were imaged by Monte Carlo simulation. The phantom A is embedded with six GNP (gold nanoparticles)-loaded cylinders with same radius (1.5mm) and height (10mm) but different Au weight concentration ranging from 0.2% to 1.2%. The phantom B is embedded with eight GNP-loaded cylinders with same Au weight concentration (1%) and height (10mm) but different radius ranging from 0.1mm to 0.8mm. At last, the reconstructed XFCT images were reconstructed by maximum likelihood expectation maximization (MLEM) with un-correction and correction, respectively. In this study, the feasibility of the proposed imaging system was demonstrated by Monte Carlo simulation.
- Shanghai Jiang
- Key Laboratory of Optoelectronics Technology and System, Ministry of Education, Chongqing University, Chongqing, China
- Mianyi Chen
- Key Laboratory of Optoelectronics Technology and System, Ministry of Education, Chongqing University, Chongqing, China
- Peng Feng
- Key Laboratory of Optoelectronics Technology and System, Ministry of Education, Chongqing University, Chongqing, China
- Peng He
- Key Laboratory of Optoelectronics Technology and System, Ministry of Education, Chongqing University, Chongqing, China
- Luzhen Deng
- Department of Radiation Physics, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
- Biao Wei
- Key Laboratory of Optoelectronics Technology and System, Ministry of Education, Chongqing University, Chongqing, China
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